Membrane Ultrastructure and T Cell Activation

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Cell-Membrane Ultrastructure

J. Appl. Phys. 30: 2038, 1959.12. FERN.A_NDEZ-MORkN, H.: Multiple objective aper-tures for high-resolution electron mnicroscopy.Abstract. J.Appl. Phys. 30: 2038, 1959.18:). FERN\.&NDEZ-MORaN;, 11.:Low-Temperature preparationi techniques for electroni microscopy of biological specimens based on rapid freezing w ith heliuni II . In Conference onFreezinglaind IDrv-illg o...

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Cell-Membrane Ultrastructure

J. Appl. Phys. 30: 2038, 1959.12. FERN.A_NDEZ-MORkN, H.: Multiple objective aper-tures for high-resolution electron mnicroscopy.Abstract. J.Appl. Phys. 30: 2038, 1959.18:). FERN\.&NDEZ-MORaN;, 11.:Low-Temperature preparationi techniques for electroni microscopy of biological specimens based on rapid freezing w ith heliuni II . In Conference onFreezinglaind IDrv-illg o...

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B and T Lymphocyte Attenuator is a Target of miR-155 during Naive CD4+ T Cell Activation

Background: MicroRNA-155 (miR-155) is upregulated during T cell activation, but the exact mechanisms by which it influences CD4+ T cell activation remain unclear. Objective: To examine whether the B and T lymphocyte attenuator (BTLA) is a target of miR-155 during naïve CD4+ T cell activation. Methods: Firefly luciferase reporter plasmids pEZX-MT01-wild-type-BTLA and pEZX-MT01-mutant-BTLA were ...

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Functional Implications of Plasma Membrane Condensation for T Cell Activation

The T lymphocyte plasma membrane condenses at the site of activation but the functional significance of this receptor-mediated membrane reorganization is not yet known. Here we demonstrate that membrane condensation at the T cell activation sites can be inhibited by incorporation of the oxysterol 7-ketocholesterol (7KC), which is known to prevent the formation of raft-like liquid-ordered domain...

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Mycobacterium tuberculosis Membrane Vesicles Inhibit T Cell Activation.

Mycobacterium tuberculosis utilizes multiple mechanisms to evade host immune responses, and inhibition of effector CD4+ T cell responses by M. tuberculosis may contribute to immune evasion. TCR signaling is inhibited by M. tuberculosis cell envelope lipoglycans, such as lipoarabinomannan and lipomannan, but a mechanism for lipoglycans to traffic from M. tuberculosis within infected macrophages ...

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ژورنال

عنوان ژورنال: Frontiers in Immunology

سال: 2018

ISSN: 1664-3224

DOI: 10.3389/fimmu.2018.02152